Thorne PharmaGABA-250

Thorne PharmaGABA – Natural GABA for Sleep, Stress Relief & Muscle Support

Thorne PharmaGABA delivers a clinically studied, natural form of gamma-aminobutyric acid (GABA)—the brain’s primary calming neurotransmitter—to support stress management, restful sleep, focused relaxation, and physical performance*.

Clinical studies show that natural PharmaGABA helps decrease stress-related beta brain waves while increasing alpha waves, creating a deep sense of physical relaxation without mental fog or sedation.* This unique brain-wave shift promotes calm alertness, making PharmaGABA useful both during high-stress periods and before sleep.*

Additional research demonstrates measurable physiological markers of relaxation, including reduced pupil diameter, lowered heart rate, and decreased levels of salivary cortisol and chromogranin A, two well-recognized biomarkers of stress.* Studies also indicate that GABA can enhance sleep quality*.

In a head-to-head, double-blind clinical trial, synthetic GABA failed to demonstrate these benefits, underscoring the importance of PharmaGABA’s natural, fermentation-derived form*.

Muscle & Performance Support

PharmaGABA has also been studied for its role in muscle development and recovery*. In a 12-week study, men who supplemented with whey protein plus 100 mg of PharmaGABA experienced a significantly greater increase in lean muscle mass compared to those using whey protein alone, when combined with regular strength training.* This makes PharmaGABA a valuable option for sports performance and recovery support*.

Naturally Fermented for Superior Activity

The natural GABA in Thorne’s PharmaGABA is produced through a fermentation process using Lactobacillus hilgardii—the same beneficial bacteria used to ferment cabbage in traditional kimchi. This natural production method is a key reason PharmaGABA performs differently than synthetic GABA.*

Available Strengths

• PharmaGABA-100 – 100 mg natural GABA per capsule

• PharmaGABA-250 – 250 mg natural GABA per capsule

Both formulas are non-habit forming and suitable for daily use.

Key Benefits

• Supports restful sleep*

• Helps reduce mental and physical stress*

• Promotes calm focus and relaxed alertness*

• Encourages healthy brain-wave balance*

• Supports muscle mass and athletic performance*

• Clinically studied natural (not synthetic) GABA

• Non-habit forming

• Naturally fermented with Lactobacillus hilgardii

• Manufactured by Thorne

Ideal For

• Sleep support*

• Stress and nervous system balance*

• Sports performance and recovery*

• Individuals seeking calm focus without sedation*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.